Craig Venter has his own scientific institute. He led the private effort to sequence the human genome and was one of Time Magazine's 2007 most important people. And he's been building new life. He builds chromosomes from scratch, inserts the new chromosomes in bacteria, and then "boots up" the organisms.
The DNA he produces in his laboratory are the largest molecules ever created by people and he can individually determine what DNA to include and which to exclude. He can put in junk DNA that, when decoded, simply spells his own name, or is a poem. But, most importantly, he's working to build in code that can force the little bugs into becoming solar-powered crude oil factories.
The new organisms, which Venter says should be multiplying in the lab in the next 18 months, would need high concentrations of CO2 (say, from the smokestack of a coal plant) to convert it to oil at maximum efficiencies. He can alter the octane of the fuel by altering the genes of the organism and, by selecting the best of thousands of molecules, he can "unnaturally select" the most efficient oil producers.
They're calling it 4th generation biofuel, and you can expect that it will be only the first application of this fascinating and somewhat alarming new technology. You can hear Venter himself explain the possibilities of this new technology with Chris Anderson at the recent TED conference in the video above.
Via TED

written by James, March 11, 2008
written by Ivan Hajnal, March 11, 2008
and the work is actually pointed towards answering what the minimal requirements are for a self-replicating cell...
roger?
written by EV, March 11, 2008
written by Ean, March 12, 2008
written by blah, March 12, 2008
written by J, March 12, 2008
Lol someone who is Afraid of GMOs. Roflcopter.
written by ben, March 12, 2008
net change in CO2 concentration = 0 !
written by Tim, March 12, 2008
written by obvious answer, March 12, 2008
1) it gets rid of co2
2) it makes oil
What a dumb question.
written by iamacyborg, March 12, 2008
written by tim, March 12, 2008
dude. that was funny. new keyboard funny.
thanks. :)
written by Olivier, March 12, 2008
written by jas, March 12, 2008
written by G$, March 12, 2008
$0.02,
G...
written by Daniel, March 12, 2008
written by Some Guy, March 12, 2008
you are a blithering idiot. Just thought you might not already know that.
written by john, March 12, 2008
written by Rick, March 12, 2008
James, this is an environmentalists dream come true. In this scheme, carbon dioxide sequestered from the environment is used to make an eventual oil product. That oil product when burned re-releases CO2 into the environment. Since no process is 100% efficient, the oil producing bioreactors must require more environmental CO2 than is released by burning. Assuming no fossil fuels are needed to keep the reactor running, it is thus carbon neutral, if not carbon negative. The only reason you would hate that is a knee-jerk reaction to all things related to the word oil.
Same goes for GMOs. Whether you like it or not, genetic modification is taking place. It's no different from building organic molecules with chemistry, no different than building machines from metals. It's a new technology in a new medium, that has both risks and rewards. Yes, we polluted the world with machines, yes we polluted the world with chemicals, but we've made plants grow in deserts to feed the starving, we've made chemicals that cure the sick. If you have such a problem with technology, ask yourself why you're using a computer, largely composed of oil products and consuming electricity.
Your knee jerk reaction to the word GMO is firmly rooted in ignorance. Take a biology course and step away from the propaganda. Please.
written by Pat, March 12, 2008
**Cue 'no one cares' with another "shut up hippie" gem**
But that being said, I'm with Rick on the knee-jerk reaction to GMO's, even though I don't agree with some of your other comments. Bashing bioengineering is like bashing computer engineering. A criticism so sweeping and vague makes me think that not much effort has gone into understanding it, since it's a process that can be used for good or bad.
written by durr, March 12, 2008
the good thing about running out of fossil fuels was that people would be forced to stop creating oil-based things, because it is only another step before creating even bigger plastic trash mountains.
sriously, i have nothing against stoppoing greenhouse gases and reducing co2 levels, but if we keep on doing the kind of things that we do at the rate we are doing it, because of capitalists, we´re gonna crash even harder.
dont come at me with "youre using a computer with plastic components", i think that computers are not a waste. what is a huge waste is billions of plastic bottles being produced, billions of useless plastic things being produced for the sole reason that it makes it cheaper for capitalists.
so basically, in a nutshell, this is a capitalist´s dream come true. the environment can stand their destruction for more time, more money for them, but then what? when will you start thinking about the long term effects of using things that you dont really need?
isnt this dependency on plastic a little scary?
written by durr, March 12, 2008
when your drug adict friend runs out of ingredients that he needs to keep constructing meth in his lab, dont you get happy? why would you be happy if he found another way to make those ingredients infinite? do you get my point?
written by sugar man, March 12, 2008
Hmm, but then we'd run the risk of too much oxygen and we'd all get really high and die.
The material choices and energy concerns at the time of invention were clever but not wise.
Always good to stay in the cycle of life, until someone figures out that the little bits of data that make up the planet are valuable enough that we should get some redundancy for it. But that would be I dunno, a good idea?
written by woog, March 12, 2008
The economy is going to collapse if we don't have fuel. This is not debatable. It's already started.
Genetically modified organisms aren't the devil. You're discrediting your (our) side of the fence with your luddite insecurities. Like it or not, time and tech WILL march on. You can either be a part of the discussion or you can be sidelined.
written by Mike, March 12, 2008
Though this bacteria would have to be put in cities to prevent large increases in local air-pollution and thus more lung-disease, etc. As the infrastructure for fossil fuel burning vehicles continues, and as more and more people are driving in cities (particularly in America, where there is no real public transportation), and as populations continue to rise world-wide, this could possibly drive up net CO2 in the atmosphere, as a certain concentration of the greenhouse gas is required for the bacteria to be viable...
written by Rick, March 12, 2008
The reality is that every single car that runs on fossil fuels will need to be retrofitted or discarded in order to adopt a new fuel. Are you going to be the one to take the car away from the single mom that needs it to take her kids to the doctor? Are you going to be the one to buy her a new fuel-cell based car? Are you going to be the one to take cars away from every consumer in America? We all have stories like her, and families that depend on us. We're not ready to fulfill your intellectual ideal of magically all moving over to clean fuel.
Going green is a process. This allows us to safely make a transition to cleaner technology.
Your thoughts that oil is like being meth addicted are quite ridiculous. I'll agree that it is sub-par for our society to continue to blow up fossilized oceanic detritus in order to propel ourselves by the same basic gas laws that govern steam engines. But there is nothing inherently evil about using oil. In the reaction of hydrocarbons with oxygen, can you show me which part of the process evil enters?
Under this type of scheme, we could be carbon neutral quite quickly. Perhaps I'm ignorant. Do you detractors propose a better solution? Ethanol has been debunked as a viable fuel source and hydrogen is still years and years away from being a viable solution. If you have some technology you're holding on to, please, enlighten the rest of us. Until then, you're just spouting rhetoric about being "addicted". If not for this technology now, then what? We wait ten more years for a better technology, and continue to spew out CO2 because this technology isn't good enough for your propaganda-laden ideals?
The reason you should be happy about gaining an infinite supply of "meth" is quite simply: because your analogy is wrong. If this technology comes to fruition, in 18 months, we are gaining more time for the development of cleaner more efficient technologies, and potentially mitigating the horrendous outpour of greenhouse gasses. This isn't a meth lab that continues to run. Petroleum is used to form the plastics that make your computers, it's an incredibly important source of carbon for the drugs that heal the sick, it powers the tractors in the vegetable fields and the trucks that move that food to your local store. That is our addiction - we have an addiction to food, to good health, to comfortable living.
So no, I don't get your point about a meth supply becoming infinite. You want to make war on health, food and quality of life, be my guest.
written by Eric, March 12, 2008
-----warning: rant below--------
Venter has a history of claiming that he or his team have made some fantastic biotech advancement, completely ignoring the legions of biologists that provide the foundation for the minor extra step he takes. The extra step which he then, of course, tries to patent.
This article talks about his private effort to sequence the human genome as if that was a good thing. If Venter had succeeded in beating the governmental/non-profit group to that goal, his plan was to then require licensing fees from anybody who wanted to use human sequence data.
I can't even begin to describe how insanely awful that would have been, not just because of the impediment to research, but because it is just plain wrong to say that somebody can own human genes.
To put Venter's money-thirst in a historical context for you molecular biologists out there, consider the fact that he tried to patent cDNA. Yes, as in any cDNA. Can you imagine trying to do your research if you had to pay a licensing fee every time you wanted to make cDNA? Think about that the next time you read about the oh so wonderful Craig Venter.
written by Rick, March 12, 2008
written by Genki, March 12, 2008
written by nick, March 12, 2008
written by Jay, March 12, 2008
written by Thomas, March 12, 2008
written by Hugo, March 12, 2008
written by jeremy, March 12, 2008
there will be meth (oil) enough for all of us, hell we may need to engineer ourselves a way to consume more oil.
Oil=dead things rotting in the ground
dead things=not life
not life=not good
written by jeremy, March 12, 2008
It will be uncomfortable for a while, but most diets are.
written by Wow, March 12, 2008
written by destroy, March 12, 2008
What about the tech. Can someone use it to create the ultimate virus? Or accidentally create zombies, even?
written by blah, March 12, 2008
There is no doubt that Venter is a) a huge jerk and b) interested in profits. There is also no doubt that when the guy says he can do something, he often does it... better and faster than everyone else.
written by dbgarf, March 12, 2008
some engineers are sorely lacking in the ethics department and create dangerous technology. some political activists are sorely lacking in the knowledge department and form ideologies that have no relationship with reality.
if you are an engineer who does not consider the consequences of the technology you produce you have a problem. if you are a political activist who does not attempt to learn (at least at a broad level) what the engineers know you have a problem.
there's too much knee-jerk bullshit in this thread, and lets be honest, most of it is of the political activist variety. this a technology that really is potentially dangerous but also potentially extremely beneficial. if the politically minded folks in here were authentic people they would be asking the engineers what the risks are and what they are doing to contain those risks. they wouldn't make assinine comments about meth addiction.
written by rmac, March 12, 2008
However, one of the major concerns for the future lack of oil has been/will be plastics. Some economists say that the global dependence on plastics far outweighs the global dependence on gasoline. This method could be very helpful for on that front.
written by oscar, March 12, 2008
written by justin, March 12, 2008
written by Amoeba, March 12, 2008
written by Obvious Answer, March 12, 2008
This invention can USE their boogie man for good, which they can't tolerate. (Can you imagine Freddie Kruger working at the deli slicing meat with his glove?) Anything that USES CO2 deprives them of their stick. And, on top of that, it MAKES petroleum? Oh heavens! It could reduce the price of oil, by increasing the available supply.
This just cannot happen!
written by Jonathan, March 12, 2008
Maybe all you dope smoking hippies should cut out your weed habit. It takes petroleum to process and get that crap to market. Stop killing the environmnet
you freaking stoners. (weed smoking also creates carbon monoxide when burned)
written by Tom, March 13, 2008
written by rezwits, March 13, 2008
written by Phil, March 13, 2008
written by Electron loving hippie, March 13, 2008
I'm a hypocrite that worships technology and scorns it's impact on the world around me. No matter how brilliant the mind or idea is, evil, like me, will find a better use for it. (like the atom bomb)
Maybe, just maybe, the modern definition of intelligence is what's flawed.
At least I know I'm evil. :) And I embrace it.
God is in the tv. We don't need oil, we don't need most of the world around us, there are people wearing penis gourds and eating monkeys in south america that prove that one.
The point is, we want it because we find it cool, like smoking, or meth... and one day, the masterful oblivion will be our end.
Anybody got a light? I feel like a deep inhale of more stuff that's bad for me. ooooh yeah. And the cancer forming will soon take over and destroy the world, but it's been a fun ride.
But, even I recognize that unless you stop embracing my bad habits you might parish with my ass in silicon valley.
Anybody see the sterling machine power plants in California? damn them for slowing down my sweet sweet oblivion. And I hear it doesn't use fossil fuel, the bastards.
written by ekstatek, March 16, 2008
written by Simon Tannock, March 16, 2008
written by frisbee, March 18, 2008
CO2 (and other greenhouse gasses) prove to be very poisonous to our climate. Remember, it's the one and only climate we have (!) Now every bit of CO2 added to the atmosphere coming from a fossil source, will add to the already happening climate change. In my opinion we should use all our knowledge, skills, money and laws on reducing carbon emissions in order to reach a zero emission level the sooner the better.
But how to achieve this?
First: tax all fossil CO2. I know you hate taxes, same as me. But this is not an ordinary tax. It is on a highly poisonous matter that spoils our world and that of future generations! This administration will not cooperate. Hope next one will.
Second: these taxes should help lower carbon emissions, by lowering our (carbon intensive) luxury spendings as well as by making carbon neutral alternatives economically viable.
Third: every cent of this tax income should be spend on speeding up development of carbon neutral energy sources as well as on repairing the damage carbon-emissions already have created and will create in the future.
The technique proposed by Venter will lower carbon emissions. But will it ever be carbon neutral? Only if fossil will not be the primary source of the carbon needed!
His technique would depend on sunlight. Sounds like solar energy! Will these bacteria have a higher efficiency compared to the latest promising solar techniques? What size does such a factory need in order to absorb all CO2 of a fossil power plant? So, would it me more cost-effective than modern solar? Besides of that, solar doesn't require any GMO's.
By the way, in the near future why would we still be needing oil as fuel? New battery- and quick charging techniques combined with large scale production and high (carbon taxed) gasoline prices will surely make EV's the new standard!
written by ralph, March 18, 2008
the organism needs a high co2 concentration to make oil, i.e. from a coal power plant stack.
hence, when the bio-oil is burned, the carbon from the coal plant goes up in the air. obviously its better than burning both the oil and the coal, but its still nowhere near carbon neutral.
perhaps an organism that could reduce carbon already in the atmosphere would be more useful. but that would probably be technically more difficult, and i suspect that mr venter isnt particularly interested in making oil environmental at all, however he finds climate change a convienient bandwagon to sell his latest product off.
written by Tim, March 18, 2008
written by SteveOfOz, March 20, 2008
OR
I can turn the veggie oil into Biodiesel and use it in an unmodified diesel.
It would be great if we could do this without taking food away from other people though.
written by Jim E, March 22, 2008
No one knows what mutations might occur with GMOs in the wild, or how people and other other living things will react to those GMO mutations.
I suppose that one way to deal with that would be to build a solution into the GMO itself. For example, if these bacteria were built to only survive only in an environment of 50% or more of CO2, or at a temperature of 150F or more, then we wouldn't need to worry as much about unintended consequences if they were accidentally released. If release did occur, they would die.
Of course, even those traits are subject to mutation, but I think thatkind of built-in protection would make this kind of project more palatable to a lot of people.
written by maryhappyface, March 24, 2008
it's giving us more oil, true, BUT it runs off of sinlight and CO2, which basically means that it will absorb some of the bad.
yeah?
written by Oscar Easler, March 24, 2008
Lets turn all the lights off. You tree-hugging types would have us living in caves if you could get away with it. You hate oil, bet you drive a car, ride a bus, or fly in a plane. Your hypocracy knows no bounds. MINDS THAT WON'T THINK ARE A WONDERFUL THING TO WASTE!!!
written by punk, March 24, 2008
First of all, bioengineering is not going to create a bacteria that will mutate us all or destroy the world. You have been watching "I am Legend" too much.
Also. What is the point of creating MORE oil when we have been trying for so long to find a fuel that will decrease dependency on it? Either way, emissions are not really decreased because you still have to BURN the oil to obtain usable energy. And as for imacyborg's comment, way to jump from bacteria to dragons, genius. We still aren't even capable of creating tissue from scratch. good job.
Another thing: Using solar energy to make oil to get energy is ridiculously inefficient. First of all, the amount of energy we could obtain from, say, 10 square meters of solar panels at 100% efficiency-which is impossible-might power, say, five hairdryers. And using that energy to grow bacteria to make oil, which we then burn-again with very poor efficiency-to make our cars go is not an intelligent waste of resources.
Even though we don't know much about GMOs, they have the potential to be extremely helpful. It is not fair or at all intelligent to dismiss them because you associate them with, say, stem cell research. Being afraid of something because you don't understand it, or because you're biased is unbelievably stupid. Before you form an opinion, do some research, read some books, use your brain. If you can't do that, you should not be entitled to voicing your opinion.
written by Pirate Prentice, March 24, 2008
written by frisbee, March 27, 2008
Of course the idea is to reuse the CO2, but it ends up with all the CO2 going into our atmosphere and oceans. The only way not making this happen is to store all of the oil made with bacteria and sunlight for ever. Great! But will anybody be willing invest in that?
Why not skip the burning of fossil fuels in the first place and make the change to alternative energy? I know it’s takes huge investments and some extra technological breakthroughs in the first place, but in the end we will be of with far less environmental damage, meaning that our future generations won’t need to pay for our quite insane way of living in luxury.
written by sighing at the world, April 18, 2008
written by gasman, April 20, 2008
written by Craig, May 15, 2008
written by MrJDL1971, June 19, 2008
written by Biggs, June 23, 2008
written by kbinla, June 25, 2008
written by mike, June 27, 2008
written by Willy, June 29, 2008
written by Charles, July 27, 2008
Also, aren't there alternatives to hydrocarbon fuels, such as nuclear and hydro-electric, the latter perhaps being the most practical form of renewable energy available today?
written by dave Micro student, October 01, 2008
I would encourage people to pick up the latest magazine of Scientific American entitled "FUEL OR WATER" Nuclear power will solve many pollution problems and bring down the cost of electricity, however it will come at a huge cost of freshwater for cooling.
What people can do now is Recycle their plastic, consider diesel vehicles (they produce more power and are more effecient Just drive one you maybe suprised) and conserve our freshwater.
** another note is that electric cars are not as clean as people think. The batteries are not a renewable resource and the electricity to charge it comes from a very high polluting power plant.
:( nothing is free we have a long road ahead of us.
written by Scott, October 23, 2008
First...I'm getting sick of hearing about CO2 levels and greenhouse gas emissions. Nobody has yet explained to me how average Earth temps were lower in the geologic past when CO2 levels were higher.
Second...if I could produce a zero-emmision, completely clean powerplant tomorrow that would use water to create far more efficient energy than anything we have, say a He3 fusion power plant, everyone "green" would throw me a parade. However, do you ever stop to think of the ramifications of what you so strongly desire? Taken to it's logical extension, everyone producing highly efficient, extremely clean energy would...anyone...anyone...cause heat problems on this planet the likes of which we have never imagined.
Third...lets assume you're all right and we're on the path to destruction. Which version of commerce is going to generate the necessary leaps in technology we need to sustain a growing population? In fact, please point to a better system than capitalism for generating new advances in high-technology. I'm not in the bucket for capitalism, but it seems to me that only a system that gives serious incentive to innovate can help us if you're all right about the global environmental situation. I can't think of another current or past economic system that would do it in time.
written by your average neighborhood stalker, November 15, 2008
written by Seven, December 07, 2008
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